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For coimmunoprecipitation assays, WT human IR and L973F-IR cDNA were cloned into 3_Flag-CMV-14 mammalian expression vector (MilliporeSigma)

Abbreviations DNA: Deoxyribo Nucleic Acid DPPH: 2,2-Diphenyl-1-Picrylhydrazyl FRAP: Ferric Reducing Antioxidant Power GSHPx: Glutathione Peroxidase HPLC: High Performance Liquid Chromatography SOD: Super Oxide Dismutase TBA: Thiobarbituric Acid TPC: Total Protein Content

Thankfully, your body has a defense system: antioxidants

Animal studies involving surgically severed tendons document measurable improvements in tensile strength and tissue integrity within 14 to 21 days of administration

10.1111/j.1365-2125.2006.02690.x Summary Keywords single nucleotide polymorphism, adverse effect, methotrexate, azathioprine, cyclophosphamide, mycophenolate mofetil Citation Hamdani S, Hamijoyo L, Amalia R and Barliana MI (2025) Gene polymorphisms associated with immunosuppressant adverse effects in systemic lupus erythematosus: a narrative review

[DOI] [PubMed] [Google Scholar] 55.Jorns A., Tiedge M., Lenzen S., Munday R